Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones

Title:Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones

Volume: 10 Issue: 10

Author(s): Akbar Mobinikhaledi and Alireza Khajeh Amiri

Affiliation:

Keywords: Bis thiazolidinone heterocycles, choline chloride, green chemistry, ionic liquids, multicomponent reactions, one-pot synthesis.

Abstract: A high efficient and environmentally friendly procedure for the production of bis thiazolidinones has been developed. This synthetic approach involves the simple condensation of an appropriate dialdehyde and N,N'-diarylthioureas with chloroacetyl chloride in eutectic salts as a promoter and solvent at 80 ^°C. All products were obtained in good to excellent yields. Structures of these compounds were established on the basis of IR, ¹H-NMR, ¹³C-NMR and by elemental analysis.

Cite this article as:

Mobinikhaledi Akbar and Amiri Khajeh Alireza, Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones, Letters in Organic Chemistry 2013; 10 (10) . https://dx.doi.org/10.2174/157017861131000059