Abstract
Glucose is an important molecule for metabolism. It is more actively taken up in tumor cells than in normal cells, thus making it possible to detect the tumor. Radiolabeled glucose derivates have been successfully employed for tumor imaging for several decades. This review focuses on the development of various radiolabeled glucose derivatives as tumor imaging probes with single photon emission computed tomography (SPECT) and positron emission tomography (PET) and discusses basic research data, current status and future prospects of this class of imaging agents.
Keywords: Glucose derivatives, PET, radiotracers, SPECT, tumor imaging.
Current Medicinal Chemistry
Title:Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET
Volume: 21 Issue: 1
Author(s): T. Liu, J. Zhang, X. Wang, J. Yang, Z. Tang and J. Lu
Affiliation:
Keywords: Glucose derivatives, PET, radiotracers, SPECT, tumor imaging.
Abstract: Glucose is an important molecule for metabolism. It is more actively taken up in tumor cells than in normal cells, thus making it possible to detect the tumor. Radiolabeled glucose derivates have been successfully employed for tumor imaging for several decades. This review focuses on the development of various radiolabeled glucose derivatives as tumor imaging probes with single photon emission computed tomography (SPECT) and positron emission tomography (PET) and discusses basic research data, current status and future prospects of this class of imaging agents.
Export Options
About this article
Cite this article as:
Liu T., Zhang J., Wang X., Yang J., Tang Z. and Lu J., Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET, Current Medicinal Chemistry 2014; 21 (1) . https://dx.doi.org/10.2174/09298673113209990254
DOI https://dx.doi.org/10.2174/09298673113209990254 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Beneficial Extracardiac Effects of Cardiovascular Medications
Current Cardiology Reviews The Role of Survivin for Radiation Oncology: Moving Beyond Apoptosis Inhibition
Current Medicinal Chemistry Update on Statins: Hope for Osteoporotic Fracture Healing Treatment
Current Drug Targets Connexins as Precocious Markers and Molecular Targets for Chemical and Pharmacological Agents in Carcinogenesis
Current Medicinal Chemistry The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum
Current Neuropharmacology Quinoline as a Privileged Scaffold in Cancer Drug Discovery
Current Medicinal Chemistry Phytochemistry and Pharmacognosy of Naturally Occurring Prenyloxyanthraquinones
Current Drug Targets Evolution of the Strategies for Screening and Identifying Human Tumor Antigens
Current Protein & Peptide Science The Clinical Impact of Quantitative Cell-free DNA, KRAS, and BRAF Mutations on Response to Anti-EGFR Treatment in Patients with Metastatic Colorectal Cancer
Current Pharmaceutical Design A Critical Review of Second-Generation Anti-EGFR Monoclonal Antibodies in Metastatic Colorectal Cancer
Current Drug Targets Interventional Radiology in Paediatrics
Current Pediatric Reviews Currently Used Antimycotics: Spectrum, Mode of Action and Resistance Occurrence
Current Drug Targets Heat Shock Proteins as Prognostic Markers of Cancer
Current Cancer Drug Targets Therapy Related Markers and Response Prediction Towards Multimodal Treatment of Carcinomas of the Upper Gastrointestinal Tract
Current Pharmacogenomics and Personalized Medicine Structure-Activity Relationship Analyses of Glycyrrhetinic Acid Derivatives as Anticancer Agents
Mini-Reviews in Medicinal Chemistry Natural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis
Current Pharmaceutical Biotechnology Synthesis of Combretastatin A-4 Analogs and their Biological Activities
Anti-Cancer Agents in Medicinal Chemistry Pregabalin in Neuropathic Pain: Evidences and Possible Mechanisms
Current Neuropharmacology MicroRNAs (miRNAs) as Biomarker(s) for Prognosis and Diagnosis of Gastrointestinal (GI) Cancers
Current Pharmaceutical Design Current Status and Future Perspectives of Chemoprevention in Head and Neck Cancer
Current Cancer Drug Targets