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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Multicomponent Reactions for the Synthesis of Functionalized Imidazoles

Author(s): Samereh Seyfi, Zinatossadat Hossaini and Faramarz Rostami-Charati

Volume 16, Issue 8, 2013

Page: [652 - 656] Pages: 5

DOI: 10.2174/13862073113169990005

Price: $65

Abstract

An efficient synthesis of functionalized tetrahydroimidazoles via a one-pot tandem reaction between ninhydrin, primary alkylamines, arylisocyanates or arylisothiocyanates, acetylenic esters and triphenylphosphine is described.

Keywords: Arylisothiocyanates, dialkyl acetylenedicarboxylates, multi component reaction, ninhydrin, primary amine.


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