Generic placeholder image

Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Non-Degenerate Graphical Representation of DNA Sequences and its Applications to Phylogenetic Analysis

Author(s): Yan Yang, Yingying Zhang, Meiduo Jia, Chun Li and Liangyu Meng

Volume 16, Issue 8, 2013

Page: [585 - 589] Pages: 5

DOI: 10.2174/1386207311316080001

Price: $65

Abstract

In this paper, we propose a new 3-D graphical representation of a DNA sequence and prove that it has two properties: (1) there is no circuit in the graph; (2) there exists a one-to-one correspondence between a DNA sequence and the graph. These properties guarantee it has nondegeneracy. Based on the 3-D graphical representation, we characterize a DNA sequence by a 12-dimensional vector whose components are normalized ALE-indexes of the corresponding L/L matrices. The proposed approach is tested by the phylogenetic analysis on three datasets, and the experimental assessment demonstrates its efficiency.

Keywords: ALE-index, DNA, graphical representation, nondegeneracy, phylogenetic analysis.

Next »

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy