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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5230
ISSN (Online): 1875-614X

Measurement of Serum Monoamine Oxidase in Lichen Planus Patients and Its Clinical Significance

Author(s): Jianguo Huang, Qiying Gong and Guiming Li

Volume 13, Issue 1, 2014

Page: [64 - 67] Pages: 4

DOI: 10.2174/18715230113129990017

Price: $65

Abstract

Objective: To study the role of serum Monoamine oxidase (MAO) in Lichen planus(LP). Methods: 82 cases of Lichen planus patients and 35 healthy controls were selected in the investigation. The total serum MAO levels were measured. Results: The levels of serum MAO in Lichen planus patients were significantly higher than those in healthy controls (P<0.01). The severity of Lichen planus was not correlated with serum MAO levels (r =0.4873, t=0.73, p>0.05). Conclusion: According to the findings, there might be a coincidence of MAO and lichen planus. However, further studies are required to clarify the immunological mechanisms which are responsible for MAO synthesis during immunoreaction.

Keywords: Lichen planus, measurement, mechanism, monoamine oxidase, serum.


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