Abstract
Microdialysis is an excellent sampling technique for continuous monitoring of endogenous and exogenous compounds in the extracellular fluid. This technique has several advantages compared with conventional methods. Accordingly, this technique is extensively applied to study pharmacokinetics and pharmacodynamics both in experimental animals and human. In this mini-review, various topics related to microdialysis for the last five years will be discussed on its benefits. With the development of microdialysis technique and increasing number of applications of microdialysis for human study, this technique seems to play an important role in clinical practice, for example, bedside microdialysis as drug monitoring or diagnostic of disease.
Keywords: microdialysis, pharmacokinetics, pharmacodynamics, experimental animal, human
Current Pharmaceutical Analysis
Title: Microdialysis as an Excellent Sampling Approach for Biomedical Analysis
Volume: 1 Issue: 2
Author(s): Mihoko N. Nakashima, Mitsuhiro Wada and Kenichiro Nakashima
Affiliation:
Keywords: microdialysis, pharmacokinetics, pharmacodynamics, experimental animal, human
Abstract: Microdialysis is an excellent sampling technique for continuous monitoring of endogenous and exogenous compounds in the extracellular fluid. This technique has several advantages compared with conventional methods. Accordingly, this technique is extensively applied to study pharmacokinetics and pharmacodynamics both in experimental animals and human. In this mini-review, various topics related to microdialysis for the last five years will be discussed on its benefits. With the development of microdialysis technique and increasing number of applications of microdialysis for human study, this technique seems to play an important role in clinical practice, for example, bedside microdialysis as drug monitoring or diagnostic of disease.
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Cite this article as:
Nakashima N. Mihoko, Wada Mitsuhiro and Nakashima Kenichiro, Microdialysis as an Excellent Sampling Approach for Biomedical Analysis, Current Pharmaceutical Analysis 2005; 1 (2) . https://dx.doi.org/10.2174/1573412054022707
DOI https://dx.doi.org/10.2174/1573412054022707 |
Print ISSN 1573-4129 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-676X |
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