One-Pot Synthesis of 2,4,6-Triarylpyridines by the Oxidative Cyclocondensation of Benzaldehydes, Aromatic Alkynes and Ammonium Bifluoride

Ping      Wang; Ruimao      Hua; Chao-Jun      Li

doi:10.2174/157017941004150310102446

Abstract

An efficient and one-pot synthesis of 2,4,6-triarylpyridines by palladium-catalyzed cyclocondensation of benzaldehydes, terminal aromatic alkynes and ammonium bifluoride in the presence of tert-butyl peroxide (TBP) as oxidant is developed.

Keywords: Aromatic alkyne, ammonium bifluoride; benzaldehyde, cyclocondensation, triarylpyridines.

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Title:One-Pot Synthesis of 2,4,6-Triarylpyridines by the Oxidative Cyclocondensation of Benzaldehydes, Aromatic Alkynes and Ammonium Bifluoride

Volume: 10 Issue: 4

Author(s): Ping Wang, Ruimao Hua and Chao-Jun Li

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Keywords: Aromatic alkyne, ammonium bifluoride; benzaldehyde, cyclocondensation, triarylpyridines.

Abstract: An efficient and one-pot synthesis of 2,4,6-triarylpyridines by palladium-catalyzed cyclocondensation of benzaldehydes, terminal aromatic alkynes and ammonium bifluoride in the presence of tert-butyl peroxide (TBP) as oxidant is developed.

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Wang Ping, Hua Ruimao and Li Chao-Jun, One-Pot Synthesis of 2,4,6-Triarylpyridines by the Oxidative Cyclocondensation of Benzaldehydes, Aromatic Alkynes and Ammonium Bifluoride, Current Organic Synthesis 2013; 10 (4) . https://dx.doi.org/10.2174/157017941004150310102446

DOI https://dx.doi.org/10.2174/157017941004150310102446	Print ISSN 1570-1794
Publisher Name Bentham Science Publisher	Online ISSN 1875-6271