Copper and Iron-assisted Palladium-catalyzed Direct Arylation of Azoles with Arylboronic Acids under Ligand and Base-free Conditions

Title:Copper and Iron-assisted Palladium-catalyzed Direct Arylation of Azoles with Arylboronic Acids under Ligand and Base-free Conditions

Volume: 10 Issue: 9

Author(s): Xiang-Mei Wu and Qiu-Xian Shen

Affiliation:

Keywords: Palladium, copper, iron, arylation, arylboronic acid.

Abstract: The direct arylation of azoles with arylboronic acids is effectively promoted by PdCl2 in the presence of copper and iron salts under ligand and base-free conditions. This reaction can be applied to heterocycles such as benzothiazole, benzoxazole, 1-methylbenzimidazole and 4,5-dimethylthiazole with moderate to good yields.

Cite this article as:

Wu Xiang-Mei and Shen Qiu-Xian, Copper and Iron-assisted Palladium-catalyzed Direct Arylation of Azoles with Arylboronic Acids under Ligand and Base-free Conditions, Letters in Organic Chemistry 2013; 10 (9) . https://dx.doi.org/10.2174/15701786113109990034