Abstract
Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent such as cadmium chloride under environment friendly conditions has been developed.
Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.
Letters in Organic Chemistry
Title:Development of Safe and Economical Synthesis of Isoxazole
Volume: 10 Issue: 9
Author(s): Lakshmikant H. Nitlikar and Devanand B. Shinde
Affiliation:
Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.
Abstract: Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent such as cadmium chloride under environment friendly conditions has been developed.
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Cite this article as:
Nitlikar H. Lakshmikant and Shinde B. Devanand, Development of Safe and Economical Synthesis of Isoxazole, Letters in Organic Chemistry 2013; 10 (9) . https://dx.doi.org/10.2174/15701786113109990032
DOI https://dx.doi.org/10.2174/15701786113109990032 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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