Investigation of Reactions Between Binucleophilic Reagents with 2-(2-Oxindolin-3-ylidene)malononitrile Derivatives

Title:Investigation of Reactions Between Binucleophilic Reagents with 2-(2-Oxindolin-3-ylidene)malononitrile Derivatives

Volume: 10 Issue: 7

Author(s): Mohammad Seifi and Hassan Sheibani

Affiliation:

Keywords: Hydrazones, 2-(2-oxindolin-3-ylidene)malononitriles, 4-substituted thiosemicarbazides.

Abstract: Nucleophilic addition of hydrazines and thiosemicarbazide to the 2-(2-oxoindolin-3-ylidene) malononitrile derivatives 1, followed by elimination of malononitrile, lead to 3-(2-arylhydrazono)indolin-2-ones and 1-(2-oxoindolin-3- ylidene)thiosemicarbzides respectively. Also the reaction of compounds 1 with 4-substituted thiosemicarbazides, followed by elimination and cyclization, afforded spiro(indolone-3,2´-[1,3,4]thiadiazol)-2-ones. So all of these nucleophilic reactions with isatin and substituted isatins released the same products.

Cite this article as:

Seifi Mohammad and Sheibani Hassan, Investigation of Reactions Between Binucleophilic Reagents with 2-(2-Oxindolin-3-ylidene)malononitrile Derivatives, Letters in Organic Chemistry 2013; 10 (7) . https://dx.doi.org/10.2174/1570178611310070004