Abstract
Synthesis of triazole based unnatural amino acids, triazole bis-amino acids and β-amino triazole has been described via stereo and regio-selective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW irradiation conditions. The developed method is applicable to a broad substrate scope and has significant potential for the synthesis of triazole modified unnatural amino acids.
Keywords: Sulfamidates, Click chemistry, Unnatural amino acids, Triazole, Microwave.
Current Organic Chemistry
Title:Synthesis of Unnatural Amino Acids via Microwave-assisted Regio-selective One-pot multi-component Reactions of Sulfamidates
Volume: 17 Issue: 20
Author(s): Nasir B. R. Baig and Rajender S. Varma
Affiliation:
Keywords: Sulfamidates, Click chemistry, Unnatural amino acids, Triazole, Microwave.
Abstract: Synthesis of triazole based unnatural amino acids, triazole bis-amino acids and β-amino triazole has been described via stereo and regio-selective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW irradiation conditions. The developed method is applicable to a broad substrate scope and has significant potential for the synthesis of triazole modified unnatural amino acids.
Export Options
About this article
Cite this article as:
Baig B. R. Nasir and Varma S. Rajender, Synthesis of Unnatural Amino Acids via Microwave-assisted Regio-selective One-pot multi-component Reactions of Sulfamidates, Current Organic Chemistry 2013; 17 (20) . https://dx.doi.org/10.2174/13852728113179990047
DOI https://dx.doi.org/10.2174/13852728113179990047 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements