Synthetic Applications of γ-Hydroxybutenolides

William   H.   Miles

doi:10.2174/15701794113109990062

Abstract

γ-Hydroxybutenolides are readily available reagents that are useful starting materials for the synthesis of simple and complex compounds. This review will discuss the role tautomerism plays in the reactivity profile of γ-hydroxybutenolides, the major modes of reactivity of γ-hydroxybutenolides, and the application of this methodology for the synthesis of biologically important molecules.

Keywords: Diels-Alder reaction, Grignard reaction, γ-hydroxybutenolides, oxidation, reduction, synthesis, tautomerism.

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Current Organic Synthesis

Title:Synthetic Applications of γ-Hydroxybutenolides

Volume: 11 Issue: 2

Author(s): William H. Miles

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Keywords: Diels-Alder reaction, Grignard reaction, γ-hydroxybutenolides, oxidation, reduction, synthesis, tautomerism.

Abstract: γ-Hydroxybutenolides are readily available reagents that are useful starting materials for the synthesis of simple and complex compounds. This review will discuss the role tautomerism plays in the reactivity profile of γ-hydroxybutenolides, the major modes of reactivity of γ-hydroxybutenolides, and the application of this methodology for the synthesis of biologically important molecules.

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Miles H. William, Synthetic Applications of γ-Hydroxybutenolides, Current Organic Synthesis 2014; 11 (2) . https://dx.doi.org/10.2174/15701794113109990062