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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Synthesis of Unsaturated α-Acyloxybenzothiazoleamides via the Passerini Three-Component Reaction

Author(s): Fatemeh Sheikholeslami-Farahani and Ashraf S. Shahvelayati

Volume 16, Issue 9, 2013

Page: [726 - 730] Pages: 5

DOI: 10.2174/13862073113169990041

Price: $65

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Abstract

4-Benzothiazol-2-ylamino-4-oxo-2-butenoic acid, prepared from reaction of 2-aminobenzothiazole and maleic anhydride, are used as an acid component in Passerini three-component reaction, under solvent-free media, to produce unsaturated α-benzothiazole acyloxyamides in good yields.

Keywords: 2-Aminobenzothiazole, maleic anhydride, passerini reaction, solvent-free media.


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