Glutamine, Glucose and other Fuels for Cancer

Title:Glutamine, Glucose and other Fuels for Cancer

Volume: 20 Issue: 15

Author(s): Maria Victoria Ruiz-Perez, Francisca Sanchez-Jimenez, Francisco J. Alonso, Juan A. Segura, Javier Marquez and Miguel Angel Medina

Affiliation:

Keywords: Aerobic glycolysis, cancer metabolism, glutaminolysis, metabolic reprogramming, tumor microenvironment.

Abstract: Tumor cells suffer a metabolic reprogramming which allows them to use metabolic fuels (glucose, glutamine, lipids) through anabolic fates to support their enhanced proliferation and other carcinogenesis-related features. The present review tries to address and summarize the broad and growing information available about this reprogramming, whose pieces, put together, make up a complex scheme that encompasses different complexity scales, from cells to systemic networks.

Cite this article as:

Ruiz-Perez Victoria Maria, Sanchez-Jimenez Francisca, Alonso J. Francisco, Segura A. Juan, Marquez Javier and Medina Angel Miguel, Glutamine, Glucose and other Fuels for Cancer, Current Pharmaceutical Design 2014; 20 (15) . https://dx.doi.org/10.2174/13816128113199990482