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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Phospholipase A2 Inhibitors Isolated From Medicinal Plants: Alternative Treatment Against Snakebites

Author(s): Lorane I.S. Hage-Melim, Suely V. Sampaio, Carlton A. Taft and Carlos H.T.P. Silva

Volume 13, Issue 9, 2013

Page: [1348 - 1356] Pages: 9

DOI: 10.2174/1389557511313090009

Price: $65

Abstract

Many plants are used in traditional medicine as active agents against various effects of snake bites. Phospholipase A2 enzymes are commonly found in venoms of snakes of the Viperidae and Elaphidae families, which are their main components. This article presents an overview of inhibitors isolated from plants, which show antiophidian properties.

Keywords: Antivenom, Bothrops jararacussu, Flavonoids, Phospholipase A2 inhibitors, Plants, Snake venom, Snake bite.


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