Abstract
Background: Gastroparesis is a disorder characterized by delayed gastric emptying of a meal in the absence of a mechanical gastric outlet obstruction. Idiopathic gastroparesis is at least as common as diabetic gastroparesis in most case series, and the true prevalence of gastroparesis is unknown.
Results: We report here an interesting case of idiopathic gastroparesis characterized by sudden onset in a female patient. The diagnosis was confirmed by ultrasonographic study of gastric emptying and electrogastrography, by gastric endoscopy/histology, and finally by allergy tests. The disorder was found to be due to a rare cause, namely an allergic predisposition. In fact, our patient, who demonstrated an allergy to gold salts, had drunk a glass of a liqueur containing gold flakes and developed an eosinophilic aggregation in the gastric mucosa observed at gastric endoscopy/histology. The symptoms disappeared after steroid administration.
Conclusion: Our experience suggests that gastric histology and close enquiry into any history of allergy may be useful diagnostic tools in cases of idiopathic gastroparesis.
Keywords: Allergy, eosiniphilic gastritis, gold salts, Idiopathic gastroparesis.
Inflammation & Allergy - Drug Targets (Discontinued)
Title:A Mysterious Case of Gastroparesis: Could the Secret be Found in a Drink?
Volume: 12 Issue: 3
Author(s): Mariabeatrice Principi, Ranaldo Nunzio, Giuseppe Ingravallo, Giuseppe Riezzo, Elisabetta Damiani, Antonio Ferrannini, Roberta Rossi, Leonardo Resta, Enzo Ierardi and Alfredo Di Leo
Affiliation:
Keywords: Allergy, eosiniphilic gastritis, gold salts, Idiopathic gastroparesis.
Abstract: Background: Gastroparesis is a disorder characterized by delayed gastric emptying of a meal in the absence of a mechanical gastric outlet obstruction. Idiopathic gastroparesis is at least as common as diabetic gastroparesis in most case series, and the true prevalence of gastroparesis is unknown.
Results: We report here an interesting case of idiopathic gastroparesis characterized by sudden onset in a female patient. The diagnosis was confirmed by ultrasonographic study of gastric emptying and electrogastrography, by gastric endoscopy/histology, and finally by allergy tests. The disorder was found to be due to a rare cause, namely an allergic predisposition. In fact, our patient, who demonstrated an allergy to gold salts, had drunk a glass of a liqueur containing gold flakes and developed an eosinophilic aggregation in the gastric mucosa observed at gastric endoscopy/histology. The symptoms disappeared after steroid administration.
Conclusion: Our experience suggests that gastric histology and close enquiry into any history of allergy may be useful diagnostic tools in cases of idiopathic gastroparesis.
Export Options
About this article
Cite this article as:
Principi Mariabeatrice, Nunzio Ranaldo, Ingravallo Giuseppe, Riezzo Giuseppe, Damiani Elisabetta, Ferrannini Antonio, Rossi Roberta, Resta Leonardo, Ierardi Enzo and Leo Di Alfredo, A Mysterious Case of Gastroparesis: Could the Secret be Found in a Drink?, Inflammation & Allergy - Drug Targets (Discontinued) 2013; 12 (3) . https://dx.doi.org/10.2174/1871528111312030005
DOI https://dx.doi.org/10.2174/1871528111312030005 |
Print ISSN 1871-5281 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4055 |
Related Articles
-
Divergent Roles of IRS (Insulin Receptor Substrate) 1 and 2 in Liver and Skeletal Muscle
Current Medicinal Chemistry Regulation of Nociceptive Transmission at the Periphery Via TRPA1-TRPV1 Interactions
Current Pharmaceutical Biotechnology N-Substituted Aryl Sulphonamides as Potential Anti-Alzheimer’s Agents: Design, Synthesis and Biological Evaluation
Current Computer-Aided Drug Design Physiology and Therapeutic Potential of the Thymic Peptide Thymulin
Current Pharmaceutical Design Macrocyclic Inhibitors of HCV NS3-4A Protease: Design and Structure Activity Relationship
Current Topics in Medicinal Chemistry Immune Response and Immunotherapy: Live Attenuated Listeria monocytogenes (Lm)-LLO Immunotherapy for the Treatment of Prostate Cancer
Current Cancer Therapy Reviews Design and Synthesis of IMR-23, an Oxime Derived from Nitroimidazole as an Immunomodulatory Molecule
Current Drug Delivery Severe Neutropenia in a Renal Transplant Patient Suggesting an Interaction Between Mycophenolate and Fenofibrate
Current Drug Safety Is Fibroblast Growth Factor Receptor 4 a Suitable Target of Cancer Therapy?
Current Pharmaceutical Design Does Ceruloplasmin Defend Against Neurodegenerative Diseases?
Current Neuropharmacology Pharmacokinetics and Pharmacokinetic Variability of Heroin and its Metabolites: Review of the Literature
Current Clinical Pharmacology Targeting Tyrosine Kinase Receptors in Hepatocellular Carcinoma
Current Cancer Drug Targets Gold Coordination Complexes as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Oxytocin as a Potential Adjuvant Against COVID-19 Infection
Endocrine, Metabolic & Immune Disorders - Drug Targets Matrix Metalloproteinases
Current Medicinal Chemistry Preface
Current Pharmaceutical Design Prolonged Physiologic Doses of Corticosteroids for the Treatment of Severe Community Acquired Pneumonia
Current Respiratory Medicine Reviews The Effect of Cyclosporine A on Dermal Fibroblast Cell - Transcriptomic Analysis of Inflammatory Response Pathway
Current Pharmaceutical Biotechnology Cardiovascular and Metabolic Effects of Ghrelin
Current Diabetes Reviews Targeting Telomerase by Antisense-Based Approaches: Perspectives for New Anti-Cancer Therapies
Current Pharmaceutical Design