Abstract
Our aim was to investigate the influence of magnetic nanoparticles of Fe3O4/oleic acid – core/shell on the adherence to cellular and inert substrata of clinical fungal using direct and inverted optic microscopy and Confocal Laser Scanning Microscopy (CLSM). The biofilm development ability varied with the tested species (C. albicans>C. tropicalis>C. glabrata>S. cerevisiae>C. krusei>C. famata), its intensity being correlated with early germ tubes production. The magnetite nanoparticles strongly inhibited the mature biofilms development (of 48 and 72 hours) as well as the fungal adherence to the cellular substratum, suggesting that magnetic nanoparticles could be used for obtaining new materials with anti-adherence properties.
Keywords: Core/shell, Fungal biofilm, Fe3O4/oleic acid, Nanofluid, Anti-biofilm.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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