Abstract
In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
Keywords: Immunity, MAVS, mitochondria, viral infection
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued)
Title:MAVS: A New Weapon in the Fight Against Viral Infections
Volume: 7 Issue: 2
Author(s): Jose A. Boga, Maria de Ona, Santiago Melon, Marta E. Alvarez-Arguelles, Ana Morilla and Ana Coto-Montes
Affiliation:
Keywords: Immunity, MAVS, mitochondria, viral infection
Abstract: In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
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Cite this article as:
A. Boga Jose, de Ona Maria, Melon Santiago, E. Alvarez-Arguelles Marta, Morilla Ana and Coto-Montes Ana, MAVS: A New Weapon in the Fight Against Viral Infections, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) 2013; 7 (2) . https://dx.doi.org/10.2174/1872214811307020004
DOI https://dx.doi.org/10.2174/1872214811307020004 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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