Abstract
Aldehydes were respectively converted to the corresponding 2-imidazolines in good yields by the reaction with ethylenediamine using iron (III) phosphate on water under reflux condition. Furthermore nitriles were converted to the corresponding 2-imidazolines under solvent-free condition at 100 °C. Utilizing of heterogeneous and recyclable catalyst, water as a solvent and solvent-free condition is the best medium from a green chemistry standpoint.
Keywords: Green chemistry, Iron (III) phosphate, Imidazoline, Solvent-free, Water mediated, Reusability of the Catalyst, Iron (III) phosphate, Antihypertensive, Antialzimer, Antitumor
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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