Abstract
The aims of this research were to obtain improved wound dressings based on collagen (COLL), polysaccharides (dextran= DEX, diethylaminoethyl-cellulose= DEAEC), silica network and usnic acid, as quorum sensing inhibitor. FT-IR, SEM, interaction with eukaryotic cells and a novel protocol to evaluate the antimicrobial activity of the new wound dressing, firstly reported in literature were used for the characterization of fabricated wound dressings. The obtained wound dressings are not cytotoxic, do not influences the mesenchymal stem and exhibit good anti-biofilm properties. Taken together, these results are suggesting that the new systems can be safely used for local applications on the lesional tissues.
Keywords: Collagen biomaterial, Wound dressing, Usnic acid, Anti-biofilm
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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