Abstract
An ideal drug must be absolutely inert in normal conditions, providing release of active compounds only in diseased areas. Nanoengineered polymeric capsules have required features. We describe here basic methods for the fabrication of such containers and give some particular examples of their use when the drug release is triggered by the presence of the disease itself or by the soft external action, with no side effects on the adjacent tissues.
Keywords: Ideal drug carrier, Layer-by-Layer electrostatic self-assembly, Polyelectrolyte capsules, Targeted drug delivery, Triggered drug release, Bacteriorhodopsin (BR), UV irradiation of azobenzene, Biocompatibilty, Confocal laser scanning microscopy (CLSM), Nanoengineered Polymeric Capsules
Current Organic Chemistry
Title:Smart Nanoengineered Polymeric Capsules as Ideal Pharmaceutical Carriers
Volume: 17 Issue: 1
Author(s): Laura Pastorino, Svetlana Erokhina and Victor Erokhin
Affiliation:
Keywords: Ideal drug carrier, Layer-by-Layer electrostatic self-assembly, Polyelectrolyte capsules, Targeted drug delivery, Triggered drug release, Bacteriorhodopsin (BR), UV irradiation of azobenzene, Biocompatibilty, Confocal laser scanning microscopy (CLSM), Nanoengineered Polymeric Capsules
Abstract: An ideal drug must be absolutely inert in normal conditions, providing release of active compounds only in diseased areas. Nanoengineered polymeric capsules have required features. We describe here basic methods for the fabrication of such containers and give some particular examples of their use when the drug release is triggered by the presence of the disease itself or by the soft external action, with no side effects on the adjacent tissues.
Export Options
About this article
Cite this article as:
Pastorino Laura, Erokhina Svetlana and Erokhin Victor, Smart Nanoengineered Polymeric Capsules as Ideal Pharmaceutical Carriers, Current Organic Chemistry 2013; 17 (1) . https://dx.doi.org/10.2174/138527213805289088
DOI https://dx.doi.org/10.2174/138527213805289088 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Natural Bioactive Compounds as Emerging Therapeutic Molecules Against Breast Cancer: Emphasis on the Role of Phytoestrogens
Current Drug Targets Recombinant Human Insulin-Like Growth Factor-1: A New Cardiovascular Disease Treatment Option?
Cardiovascular & Hematological Agents in Medicinal Chemistry The Role of Chronic Periodontitis in Prevention and Treatment of Head and Neck Cancers
Current Cancer Therapy Reviews Benzo[a]pyrene Toxicity and Inflammatory Disease
Current Rheumatology Reviews Cellular Physiology of Mismatch Repair
Current Pharmaceutical Design ES-MDA: Enhanced Similarity-based MiRNA-Disease Association
Current Protein & Peptide Science Expression Microarray Proteomics and the Search for Cancer Biomarkers
Current Genomics Effect of Substituted Benzimidazoles and Somatostatin Analogs on the Vitality of Tumor Cell Lines and on the Oxidative Burst of Phagocytes
Letters in Drug Design & Discovery Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity
Medicinal Chemistry Modulation of k-Ras Signaling by Natural Products
Current Medicinal Chemistry New Developments and Prospective Applications for β (1,3) Glucans
Recent Patents on Biotechnology Improvement of Chemical Stability and Activities of Anthocyanins by Complexation
Current Bioactive Compounds Changes in Glutathione, Oxidative Stress and Mitochondrial Membrane Potential in Apoptosis Involving the Anticancer Activity of Cantharidin Isolated from Redheaded Blister Beetles, Epicauta hirticornis
Anti-Cancer Agents in Medicinal Chemistry Targeting the Perpetrator: Breast Cancer Stem Cell Therapeutics
Current Drug Targets (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Mammalian Nucleoside Transporters
Current Drug Metabolism Current Technological Development of Antibody Therapeutics
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) A Historical Overview of the Heterologous Expression of Mammalian UDP-Glucuronosyltransferase Isoforms Over the Past Twenty Years
Current Drug Metabolism The Challenges of Modeling Drug Resistance to Antiangiogenic Therapy
Current Drug Targets P53 and Beta-Catenin in Colorectal Cancer Progression
Current Pharmaceutical Design Is Biotechnological Next-Generation Therapeutics Promising Enough in Clinical Development to Treat Advanced Colon Cancer?
Current Pharmaceutical Biotechnology