A One-Pot Multi-Component Synthesis of N-cyclohexyl-3-arylquinoxaline- 2-amines Using ZnO Nanoparticles as a Heterogeneous Reusable Catalyst

Title:A One-Pot Multi-Component Synthesis of N-cyclohexyl-3-arylquinoxaline- 2-amines Using ZnO Nanoparticles as a Heterogeneous Reusable Catalyst

Volume: 10 Issue: 1

Author(s): Abolfazl Ziarati, Javad Safaei-Ghomi and Sahar Rohani

Affiliation:

Keywords: N-cyclohexyl-3-aryl-quinoxaline-2-amines, ZnO nanoparticles, heterogeneous catalyst, multi-component, isocyanides, reagent, toluene, diffraction peak, purity, SEM image

Abstract: A general synthetic route to synthesis of N-cyclohexyl-3-aryl-quinoxaline-2-amines has been developed using ZnO nanoparticles under mild conditions. The multi-component reactions of aldehydes, o-phenylenediamine and cyclohexyl isocyanide were carried out to afford some N-cyclohexyl-3-aryl-quinoxaline-2-amines derivatives. The present approach offers several advantages such as high yields, environmentally benign, easy purification, recovery and reusability of the catalyst.

Cite this article as:

Ziarati Abolfazl, Safaei-Ghomi Javad and Rohani Sahar, A One-Pot Multi-Component Synthesis of N-cyclohexyl-3-arylquinoxaline- 2-amines Using ZnO Nanoparticles as a Heterogeneous Reusable Catalyst, Letters in Organic Chemistry 2013; 10 (1) . https://dx.doi.org/10.2174/1570178611310010012