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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Recent Studies of Antioxidant Quinoline Derivatives

Author(s): M. Orhan Puskullu, Betul Tekiner and Sibel Suzen

Volume 13, Issue 3, 2013

Page: [365 - 372] Pages: 8

DOI: 10.2174/1389557511313030005

Price: $65

Abstract

Quinoline derivatives constitute an important class of compounds for new drug development. As a large number of experimental and theoretical studies have shown that the quinoline ring system is an important structural unit widely existing in alkaloids, therapeutics and synthetic analogues with exciting biological activities. The present review provides recent antioxidant activities covering in vivo and in vitro studies of natural and synthetic analogues, as well as the proposed mechanisms of action and structure-activity relationships.

Keywords: Antioxidant activity, free radical, quinoline, oxidative stress


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