Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents

Title:Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents

Volume: 13 Issue: 3

Author(s): Jin-Jian Lu, Jiao-Lin Bao, Guo-Sheng Wu, Wen-Shan Xu, Ming-Qing Huang, Xiu-Ping Chen and Yi-Tao Wang

Affiliation:

Keywords: Quinone, Plant, Secondary metabolites, Tumor

Abstract: Quinones are plant-derived secondary metabolites that present some anti-proliferation and anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses on the anti-cancer prospects of plant-derived quinones, namely, aloe-emodin, juglone, β-lapachol, plumbagin, shikonin, and thymoquinone. We intend to summarize their anti-cancer effects and investigate the mechanism of actions to promote the research and development of anti-cancer agents from quinones.

Cite this article as:

Lu Jin-Jian, Bao Jiao-Lin, Wu Guo-Sheng, Xu Wen-Shan, Huang Ming-Qing, Chen Xiu-Ping and Wang Yi-Tao, Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents, Anti-Cancer Agents in Medicinal Chemistry 2013; 13 (3) . https://dx.doi.org/10.2174/1871520611313030008