Expeditious Solvent-Free Synthesis of Chromene Derivatives via Three- Component Reactions of N-Nucleophiles

Title:Expeditious Solvent-Free Synthesis of Chromene Derivatives via Three- Component Reactions of N-Nucleophiles

Volume: 15 Issue: 10

Author(s): Mohammad R. Hosseini-Tabatabaei and Faramarz Rostami-Charati

Affiliation:

Keywords: 4-Hydroxy coumarin, acetylenic compounds, isoquinoline, one-pot reactions, solvent-free.

Abstract: Multicomponent reactions involving 4-hydroxycumarine, activated acetylenic compounds and N-nucleophiles under solvent-free conditions were investigated. The reactions could also be extended to quinoline or CH-acides. Substituted chromen could be obtained from this routine, which may have potential applications in drugs fields.

Cite this article as:

R. Hosseini-Tabatabaei Mohammad and Rostami-Charati Faramarz, Expeditious Solvent-Free Synthesis of Chromene Derivatives via Three- Component Reactions of N-Nucleophiles, Combinatorial Chemistry & High Throughput Screening 2012; 15 (10) . https://dx.doi.org/10.2174/138620712803901126

DOI https://dx.doi.org/10.2174/138620712803901126	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402