Microwave-Assisted Multicomponent Reactions of Alkyl Bromides: Synthesis of Thiophene Derivatives

Title:Microwave-Assisted Multicomponent Reactions of Alkyl Bromides: Synthesis of Thiophene Derivatives

Volume: 15 Issue: 10

Author(s): Faramarz Rostami-Charati, Asadollah Hassankhani and Zinatossadat Hossaini

Affiliation:

Keywords: Acetyl acetone, carbonyl compounds, dimedone, microwave conditions, thiophen.

Abstract: A series of thiophene derivatives were synthesized via one-pot multicomponent reactions of alkyl bromids, aroyl or alkanoyl isothiocyanates, 1,3-dicarbonyl compounds and secondary amins under microwave irradiation at 80 °C. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

Cite this article as:

Rostami-Charati Faramarz, Hassankhani Asadollah and Hossaini Zinatossadat, Microwave-Assisted Multicomponent Reactions of Alkyl Bromides: Synthesis of Thiophene Derivatives, Combinatorial Chemistry & High Throughput Screening 2012; 15 (10) . https://dx.doi.org/10.2174/138620712803901162

DOI https://dx.doi.org/10.2174/138620712803901162	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402