Generic placeholder image

Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

One-pot Synthesis and its Practical Application in Pharmaceutical Industry

Author(s): Wenyi Zhao and Fen-Er Chen

Volume 9, Issue 6, 2012

Page: [873 - 897] Pages: 25

DOI: 10.2174/157017912803901619

Price: $65

Abstract

Compared with conventional batch-wise process, one-pot synthesis is the “condensation” of two or more steps into one-pot operation and increasingly used in chemical process research and development in order to achieve the desired molecular complexity in ecologically and economically efficient way. One-pot synthesis can be achieved via multicomponent reaction (MCR), cascade reaction, tandem reaction, or telescoping synthetic steps. This review summarizes recent progresses in this field, covering mainly four approaches developed for the application towards one-pot organic synthesis.

Keywords: Cascade reaction, multicomponent reaction, one-pot synthesis, tandem reaction, telescoping.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy