Abstract
Sodium thiomethoxide and dimethyldisulfide will be shown to be convenient sources of methyl thiyl radicals for effecting the cis-trans double bond isomerization of oleic acid to elaidic acid residues arranged in phospholipid bilayers of the microheterogeneous aqueous environment of liposomes. The methods used for methyl thiyl radical generation encompass radiolytic and photochemical methods. The convenience of these methyl thiyl radical sources will be interpreted in terms of the turn-over numbers in the radical chain cistrans isomerization reaction of unsaturated lipids.
Keywords: Methyl thiyl radicals, Sodium thiomethoxide, Dimethyldisulfide, cis-trans isomerization, isomerization, polyunsaturated substrates, methionine, radiolytic methods, biscyanopropylpolysiloxane, microheterogeneous.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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