Abstract
Cellular in vivo imaging can reveal the induction, progression and resolution of nervous system pathology in real-time. In this review, we summarize recent research in the field to illustrate how in vivo imaging has enhanced our understanding of a variety of neurological conditions caused by trauma, degeneration, ischemia or inflammation. Finally, we look ahead and discuss how novel biosensors might help us to follow not only the cellular but also the molecular pathogenesis of neurological diseases in vivo.
Keywords: In vivo imaging, multi-photon microscopy, neurodegeneration, neurotrauma, ischemia, neuroinflammation, nervous system, biosensors, cerebral cortex, reactive oxygen species.
Current Pharmaceutical Design
Title:In Vivo Imaging of the Diseased Nervous System: An Update
Volume: 18 Issue: 29
Author(s): Catherine Sorbara, Thomas Misgeld and Martin Kerschensteiner
Affiliation:
Keywords: In vivo imaging, multi-photon microscopy, neurodegeneration, neurotrauma, ischemia, neuroinflammation, nervous system, biosensors, cerebral cortex, reactive oxygen species.
Abstract: Cellular in vivo imaging can reveal the induction, progression and resolution of nervous system pathology in real-time. In this review, we summarize recent research in the field to illustrate how in vivo imaging has enhanced our understanding of a variety of neurological conditions caused by trauma, degeneration, ischemia or inflammation. Finally, we look ahead and discuss how novel biosensors might help us to follow not only the cellular but also the molecular pathogenesis of neurological diseases in vivo.
Export Options
About this article
Cite this article as:
Sorbara Catherine, Misgeld Thomas and Kerschensteiner Martin, In Vivo Imaging of the Diseased Nervous System: An Update, Current Pharmaceutical Design 2012; 18 (29) . https://dx.doi.org/10.2174/138161212802502279
DOI https://dx.doi.org/10.2174/138161212802502279 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Editorial on the Occasion of the 20th Anniversary of Endocrine Metabolic Immune Disorders-Drug Targets Journal with a Kaleidoscopic Vision of Selected Publications
Endocrine, Metabolic & Immune Disorders - Drug Targets The Therapeutic use of the Zonulin Inhibitor AT-1001 (Larazotide) for a Variety of Acute and Chronic Inflammatory Diseases
Current Medicinal Chemistry Nitric Oxide Induced Damage and Preventive Effect of Curcumin and Quercetin on Buffalo Brain Cystatin
Current Proteomics Matrix Metalloproteinases: New Routes to the Use of MT1-MMP As A Therapeutic Target in Angiogenesis-Related Disease
Current Pharmaceutical Design Functional Interactions Between B Lymphocytes and the Innate Immune System
Infectious Disorders - Drug Targets Dihydropyridine Receptor Blockade in the Treatment of Asthma
Recent Patents on Inflammation & Allergy Drug Discovery Microbes, Immunity and Multiple Sclerosis: An Update
Current Immunology Reviews (Discontinued) S1P Regulation of Macrophage Functions in the Context of Cancer
Anti-Cancer Agents in Medicinal Chemistry Bone Marrow Mesenchymal Stem Cells: Agents of Immunomodulation and Neuroprotection
Current Stem Cell Research & Therapy The Role of P2X Receptors in Bone Biology
Current Medicinal Chemistry Are Circulating Monocytes as Microglia Orthologues Appropriate Biomarker Targets for Neuronal Diseases? (Supplementry Table)
Central Nervous System Agents in Medicinal Chemistry Phosphodiesterase Inhibitors as Therapeutics for Traumatic Brain Injury
Current Pharmaceutical Design Recent Applications of Birch Reduction in Total Synthesis of Natural Products
Current Organic Chemistry Oxysterol Derivatives of Cholesterol in Neurodegenerative Disorders
Current Medicinal Chemistry Aptamers as Innovative Diagnostic and Therapeutic Agents in the Central Nervous System
CNS & Neurological Disorders - Drug Targets Vitamin D in Acute Kidney Injury
Inflammation & Allergy - Drug Targets (Discontinued) Curcumin: Structure-Activity Relationship Towards its Role as a Versatile Multi-Targeted Therapeutics
Mini-Reviews in Organic Chemistry Part-Time α-Secretases: The Functional Biology of ADAM 9, 10 and 17
Current Alzheimer Research Use of Mesenchymal Stem Cells in Crohn's Disease and Perianal Fistulas: A Narrative Review
Current Stem Cell Research & Therapy Oral Contraceptives and Autoimmune Diseases
Current Women`s Health Reviews