Abstract
The article is an extensive review of the influence of the structure of bile acids on their hydrophobicity as expressed via the retention parameters of reverse phase chromatography and via the 1-octanol/water partition coefficients. The emphasis of the discussion is on the relationship beween the structure of the steroid skeleton of bile acids and their self-association. Finally, the lipohilicity of bile acids and its role in their interaction with biological systems is also discussed.
Keywords: Bile acids, Bile acid oxo derivatives, Hydrophobicity, Self-association.
Current Organic Chemistry
Title:Hydrophobicity and Self-association of Bile Acids with a Special Emphasis on Oxo Derivatives of 5-β Cholanic Acid
Volume: 16 Issue: 16
Author(s): Mihalj Posa
Affiliation:
Keywords: Bile acids, Bile acid oxo derivatives, Hydrophobicity, Self-association.
Abstract: The article is an extensive review of the influence of the structure of bile acids on their hydrophobicity as expressed via the retention parameters of reverse phase chromatography and via the 1-octanol/water partition coefficients. The emphasis of the discussion is on the relationship beween the structure of the steroid skeleton of bile acids and their self-association. Finally, the lipohilicity of bile acids and its role in their interaction with biological systems is also discussed.
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Cite this article as:
Posa Mihalj, Hydrophobicity and Self-association of Bile Acids with a Special Emphasis on Oxo Derivatives of 5-β Cholanic Acid, Current Organic Chemistry 2012; 16 (16) . https://dx.doi.org/10.2174/138527212802651304
DOI https://dx.doi.org/10.2174/138527212802651304 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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