Abstract
Nitrogen-containing heterocycles, and more specifically the chiral ones, possess various biological and pharmaceutical properties. Among the approaches to these compounds, the organocatalyzed asymmetric multicomponent reaction has emerged as a powerful tool. This review will focus on the later development to chiral dihydropyridines, dihydropyrimidines and quinolizidines via asymmetric organocatalyzed synthesis....
Keywords: Dihydropyridines, Dihydropyrimidines, Quinolizidines, Chiral Brønsted acids, Chiral thioureas, Proline type derivatives, multicomponent condensation, cyclization, chiral pocket, Bronsted acids
Current Organic Chemistry
Title:New Approaches to Nitrogen Containing Heterocycles: Enantioselective Organocatalyzed Synthesis of Dihydropyridines (DHP's), Quinolizidine Derivatives and Dihydropyrimidines (DHPM's)
Volume: 16 Issue: 15
Author(s): Hoai T. Pham, Isabelle Chataigner and Jean-Luc Renaud
Affiliation:
Keywords: Dihydropyridines, Dihydropyrimidines, Quinolizidines, Chiral Brønsted acids, Chiral thioureas, Proline type derivatives, multicomponent condensation, cyclization, chiral pocket, Bronsted acids
Abstract: Nitrogen-containing heterocycles, and more specifically the chiral ones, possess various biological and pharmaceutical properties. Among the approaches to these compounds, the organocatalyzed asymmetric multicomponent reaction has emerged as a powerful tool. This review will focus on the later development to chiral dihydropyridines, dihydropyrimidines and quinolizidines via asymmetric organocatalyzed synthesis....
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Pham T. Hoai, Chataigner Isabelle and Renaud Jean-Luc, New Approaches to Nitrogen Containing Heterocycles: Enantioselective Organocatalyzed Synthesis of Dihydropyridines (DHP's), Quinolizidine Derivatives and Dihydropyrimidines (DHPM's), Current Organic Chemistry 2012; 16 (15) . https://dx.doi.org/10.2174/138527212802651322
DOI https://dx.doi.org/10.2174/138527212802651322 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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