1,3,4-Oxadiazole: A Biologically Active Scaffold

Title:1,3,4-Oxadiazole: A Biologically Active Scaffold

Volume: 12 Issue: 8

Author(s): H. Khalilullah, M. J. Ahsan, Md. Hedaitullah, S. Khan and B. Ahmed

Affiliation:

Keywords: 1, 3, 4-Oxadiazole, oxadiazole, azole.

Abstract: There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antimycobecterial, antitumour, antiviral and antitubercular activities. 1,3,4-oxadiazoles constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations led to the development of new 1,3,4-oxadiazole derivatives. This review article describes the various biological activities associated with 1,3,4-oxadiazole ring system and is useful in guiding the researchers across the world working on this moiety and consequently have been instrumental in the advancement of 1,3,4-oxadiazole chemistry.

Cite this article as:

Khalilullah H., J. Ahsan M., Hedaitullah Md., Khan S. and Ahmed B., 1,3,4-Oxadiazole: A Biologically Active Scaffold, Mini-Reviews in Medicinal Chemistry 2012; 12 (8) . https://dx.doi.org/10.2174/138955712801264800