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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Efficient Synthetic Method for Phenylalanine Containing Crown Ether Ring

Author(s): Xia Tian, Fang Li, Jianrong Han, Xiaoli Zhen and Shouxin Liu

Volume 9, Issue 5, 2012

Page: [356 - 359] Pages: 4

DOI: 10.2174/157017812801264665

Price: $65

Abstract

An efficient, convenient synthesis method has been introduced for the preparation of phenylalanine containing crown ether ring by nucleophilic substitution, nitrosation and reduction reaction using benzo-crown ether and dimethyl malonate as material. The structures of the product are characterized by 1HNMR, MS and element analysis.

Keywords: Benzo-crown ether, dimethyl malonate, nitrosation, reduction, α-amino acid, synthesis, rotaxanes, catenane, supramolecular, malonate


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