Dual Action-Based Approaches to Antibacterial Agents

John   B.   Bremner; Joseph   I.   Ambrus; Siritron      Samosorn

doi:10.2174/092986707780831168

Abstract

This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)

Keywords: Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs

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Current Medicinal Chemistry

Title: Dual Action-Based Approaches to Antibacterial Agents

Volume: 14 Issue: 13

Author(s): John B. Bremner, Joseph I. Ambrus and Siritron Samosorn

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Keywords: Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs

Abstract: This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)

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Bremner B. John, Ambrus I. Joseph and Samosorn Siritron, Dual Action-Based Approaches to Antibacterial Agents, Current Medicinal Chemistry 2007; 14 (13) . https://dx.doi.org/10.2174/092986707780831168