Abstract
(+)-Zwittermicin A is a highly polar, water-soluble aminopolyol antibiotic isolated from the soil-born bacterium B. cereus with significant activity against phytopathogenic fungi. The rising interest in zwittermicin A as a “green” biopesticide, has stimulated studies of its unique biosynthesis, mechanism of action and its organic synthesis. This review summarizes the current state of this antibiotic. A main focus of this review is the description of the chemistry of this compound including its synthesis.
Keywords: Zwittermicin A, Antibiotic, Biological control, Bacillus.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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