Generic placeholder image

Current Cardiology Reviews

Editor-in-Chief

ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

Cardiotoxicity of Molecularly Targeted Agents

Author(s): Nadia Hedhli and Kerry S. Russell

Volume 7, Issue 4, 2011

Page: [221 - 233] Pages: 13

DOI: 10.2174/157340311799960636

Price: $65

conference banner
Abstract

Cardiac toxicity of molecularly targeted cancer agents is increasingly recognized as a significant side effect of chemotherapy. These new potent therapies may not only affect the survival of cancer cells, but have the potential to adversely impact normal cardiac and vascular function. Unraveling the mechanisms by which these therapies affect the heart and vasculature is crucial for improving drug design and finding alternative therapies to protect patients predisposed to cardiovascular disease. In this review, we summarize the classification and side effects of currently approved molecularly targeted chemotherapeutics.

Keywords: Cardiac toxicity, chemotherapy, cardiomyopathy, tyrosine kinases, proteasome inhibitors.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy