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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Synthesis, Photophysical and Photobiological Study of Synergic Photosensitizer:Zinc-Phthalocyanine with Ca2+ Chelating Agent

Author(s): Claure N. Lunardi, Jeane C. G. Rotta and Antonio C. Tedesco

Volume 11, Issue 7, 2007

Page: [647 - 654] Pages: 8

DOI: 10.2174/138527207780598792

Price: $65

Abstract

A novel phthalocyanine derivative containing a Ca2+ chelating agent with structure similar to EDTA has been synthesized in 3 steps. The addition of a chelating agent to the phthalocyanine macrocycle make it a synergic compound useful for PDT.

Keywords: Photoinactivation, Calcium affinity, ZnPcChel, fluorescence emission, MTT Assay

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