Recent Progress in the Discovery of New CCR5 and CXCR4 Chemokine Receptor Antagonists as Inhibitors of HIV-1 Entry. Part 2*

Title: Recent Progress in the Discovery of New CCR5 and CXCR4 Chemokine Receptor Antagonists as Inhibitors of HIV-1 Entry. Part 2*

Volume: 4 Issue: 2

Author(s): Wieslaw M. Kazmierski, Jennifer P. Peckham, Maosheng Duan, Terry P. Kenakin, Stephen Jenkinson, Kristjan S. Gudmundsson, Stephen C. Piscitelli and Paul L. Feldman

Affiliation:

Keywords: chemotherapy, transcriptase inhibitors, aids, ccr5 receptor, probe, chemokine, allosteric modulator

Abstract: This review addresses key medicinal chemistry issues relevant in the discovery and development of CCR5 and CXCR4 antagonists as anti-HIV drugs. Recent progress in the discovery and development of such antagonists, SAR and clinical status are reviewed.

Cite this article as:

Kazmierski M. Wieslaw, Peckham P. Jennifer, Duan Maosheng, Kenakin P. Terry, Jenkinson Stephen, Gudmundsson S. Kristjan, Piscitelli C. Stephen and Feldman L. Paul, Recent Progress in the Discovery of New CCR5 and CXCR4 Chemokine Receptor Antagonists as Inhibitors of HIV-1 Entry. Part 2*, Current Medicinal Chemistry - Anti-Infective Agents 2005; 4 (2) . https://dx.doi.org/10.2174/1568012053506981

DOI https://dx.doi.org/10.2174/1568012053506981	Print ISSN 1568-0126
Publisher Name Bentham Science Publisher	Online ISSN 1875-600X