Abstract
A facile two step synthesis of 3-aroylcoumarin-flavone hybrids was achieved from 7-hydroxyflavone and α- oxoketene dithioacetals. In the first step 7-hydroxyflavone was regioselectively formylated under Duff reaction conditions. Resulting 8-formyl-7-hydroxy flavones were condensed with α-oxoketene dithioacetals in the presence of a catalytic amount of piperidine to furnish 3-aroylcoumarin-flavone hybrids.
Keywords: 7-hydroxyflavone, α-oxoketene dithioacetal, 8-formyl-7-hydroxy flavones, coumrain-flaovone hybrid, duff reaction, coumarins, fluorescent, flavones, sensitizers, carbonyls
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