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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Alkyne-Azide Cycloaddition Catalyzed by Fe-Cu Nanoparticles

Author(s): Angel Garcia-Munoz, Jaime Gonzalez, Jessica Trujillo-Reyes, Raul A. Morales-Luckie, Victor Sanchez-Mendieta, Carlos Gonzalez, Aydee Fuentes and Erick Cuevas-Yanez

Volume 9, Issue 3, 2012

Page: [160 - 164] Pages: 5

DOI: 10.2174/157017812800167457

Price: $65

Abstract

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of catalytic amounts of Cu-Fe nanoparticles. The process represents many advantages because it does not require additional bases or reductants, and this is carried out under ambient pressure and temperature with good yields.

Keywords: 1,2,3-triazoles, alkynes, azides, nanoparticles, CuAAC, phenylacetylene, cycloaddition, bromide, sodium, aqueous mixture


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