Labdane Diterpenes with Highly Functionalized B Rings

I.S.      Marcos; L.      Castaneda; P.      Basabe; D.      Diez; J.G.      Urones

doi:10.2174/157019312799080044

Abstract

In this review, the natural source, structure, biological activities and the synthesis of labdanes diterpenes with highly functionalized B rings, described to date are shown. The structures for these compounds have been classified taking into account the number of oxygenated positions of the B ring. In this manner the classification has 7 groups of deoxygenated labdanes, 6 of trioxygenated and one group of the tetraoxygenated ones.

Keywords: Bioactivities, diterpenes, forskolin, labdanes, synthesis, terpenes, functionalized B-rings, adenylate cyclase, nitric oxide, erigerol

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Mini-Reviews in Organic Chemistry

Title: Labdane Diterpenes with Highly Functionalized B Rings

Volume: 9 Issue: 1

Author(s): I.S. Marcos, L. Castaneda, P. Basabe, D. Diez and J.G. Urones

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Keywords: Bioactivities, diterpenes, forskolin, labdanes, synthesis, terpenes, functionalized B-rings, adenylate cyclase, nitric oxide, erigerol

Abstract: In this review, the natural source, structure, biological activities and the synthesis of labdanes diterpenes with highly functionalized B rings, described to date are shown. The structures for these compounds have been classified taking into account the number of oxygenated positions of the B ring. In this manner the classification has 7 groups of deoxygenated labdanes, 6 of trioxygenated and one group of the tetraoxygenated ones.

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Marcos I.S., Castaneda L., Basabe P., Diez D. and Urones J.G., Labdane Diterpenes with Highly Functionalized B Rings, Mini-Reviews in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157019312799080044