The Use of Glucose as Alternative Reducing Agent in Copper-Catalyzed Alkyne-Azide Cycloaddition

Marco      A. Garcia; Zita      G. Rios; Jaime      Gonzalez; Víctor      M. Perez; Nancy      Lara; Aydee      Fuentes; Carlos      Gonzalez; David      Corona; Erick      Cuevas-Yanez

doi:10.2174/157017811799304232

Abstract

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of glucose and catalytic amounts of Fehling reagent. This process is carried out under ambient pressure and temperature with good yields

Keywords: Alkynes, azides, Fehling reagent, glucose, 1,2,3-triazoles, copper, pressure, temperature, triazole, sodium

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Letters in Organic Chemistry

Title: The Use of Glucose as Alternative Reducing Agent in Copper-Catalyzed Alkyne-Azide Cycloaddition

Volume: 8 Issue: 10

Author(s): Marco A. Garcia, Zita G. Rios, Jaime Gonzalez, Víctor M. Perez, Nancy Lara, Aydee Fuentes, Carlos Gonzalez, David Corona and Erick Cuevas-Yanez

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Keywords: Alkynes, azides, Fehling reagent, glucose, 1,2,3-triazoles, copper, pressure, temperature, triazole, sodium

Abstract: 1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of glucose and catalytic amounts of Fehling reagent. This process is carried out under ambient pressure and temperature with good yields

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A. Garcia Marco, G. Rios Zita, Gonzalez Jaime, M. Perez Víctor, Lara Nancy, Fuentes Aydee, Gonzalez Carlos, Corona David and Cuevas-Yanez Erick, The Use of Glucose as Alternative Reducing Agent in Copper-Catalyzed Alkyne-Azide Cycloaddition, Letters in Organic Chemistry 2011; 8 (10) . https://dx.doi.org/10.2174/157017811799304232