Microwave-Assisted Synthesis of Novel Tetra-O-acetyl-β-D-glucopyranosyl Thiosemicarbazones of Substituted Isatins

Nguyen      D. Thanh; Nguyen      T.K. Giang

doi:10.2174/157017811796504918

Abstract

Some new substituted isatin (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazones were synthesized by reaction between 2,3,4,6-tetra-O-acetyl-bgr;-D-glucopyranosyl thiosemicarbazide and corresponding substituted isatins using conventional and microwave-assisted heating method. It is shown that the latter gave higher yields of products.

Keywords: Glucopyranosyl, isatin, microwave-assisted, monosaccharide, thiosemicarbazide, thiosemicarbazones, saccharides, antioxidant, antimicrobial, tuberculostatic

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Letters in Organic Chemistry

Title: Microwave-Assisted Synthesis of Novel Tetra-O-acetyl-β-D-glucopyranosyl Thiosemicarbazones of Substituted Isatins

Volume: 8 Issue: 7

Author(s): Nguyen D. Thanh and Nguyen T.K. Giang

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Keywords: Glucopyranosyl, isatin, microwave-assisted, monosaccharide, thiosemicarbazide, thiosemicarbazones, saccharides, antioxidant, antimicrobial, tuberculostatic

Abstract: Some new substituted isatin (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazones were synthesized by reaction between 2,3,4,6-tetra-O-acetyl-bgr;-D-glucopyranosyl thiosemicarbazide and corresponding substituted isatins using conventional and microwave-assisted heating method. It is shown that the latter gave higher yields of products.

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D. Thanh Nguyen and T.K. Giang Nguyen, Microwave-Assisted Synthesis of Novel Tetra-O-acetyl-β-D-glucopyranosyl Thiosemicarbazones of Substituted Isatins, Letters in Organic Chemistry 2011; 8 (7) . https://dx.doi.org/10.2174/157017811796504918