Abstract
The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.
Keywords: Cyanine, fluorescence, FRET, imaging, optical, probe, rhodamine, near-infrared (NIR) region, near-infrared (NIR) dyes, Fluorescent Dyes, Cyanine Dyes
Current Organic Synthesis
Title: Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging
Volume: 8 Issue: 4
Author(s): Donald D. Nolting, John C. Gore and Wellington Pham
Affiliation:
Keywords: Cyanine, fluorescence, FRET, imaging, optical, probe, rhodamine, near-infrared (NIR) region, near-infrared (NIR) dyes, Fluorescent Dyes, Cyanine Dyes
Abstract: The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.
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Cite this article as:
D. Nolting Donald, C. Gore John and Pham Wellington, Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging, Current Organic Synthesis 2011; 8 (4) . https://dx.doi.org/10.2174/157017911796117223
DOI https://dx.doi.org/10.2174/157017911796117223 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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