Abstract
In this article, a mild and efficient protocol for the tetrahydropyranylation and tetrahydrofuranylation of various aliphatic and benzylic alcohols and phenols into their corresponding THP and THF ethers (with 3,4-dihydro- 2H-pyran, DHP and 2,3-dihydrofuran, DHF) has been developed using a catalytic amount of anhydrous FePO4 at room temperature and relatively short reaction times in good to excellent yields.
Keywords: Alcohols, anhydrous FePO4, deprotection, phenols, protection, THF ethers, THP ethers, hydroxyl groups, benzylic alcohols, tetrahydropyranylation
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