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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Peptide Array-Based Peptide-Cell Interaction Analysis

Author(s): Ryuji Kato, Chiaki Kaga, Kei Kanie, Mitoshi Kunimatsu, Mina Okochi and Hiroyuki Honda

Volume 8, Issue 2, 2011

Page: [171 - 177] Pages: 7

DOI: 10.2174/157019311795177790

Price: $65

Abstract

Peptide arrays represent a powerful research tool, especially for the development of medical applications to screen peptides for the replacement of animal-derived proteins. This minireview focuses on the applicability of cellulose-bound peptide arrays to assay peptide- cell interactions. Moreover, the successful combination of peptide array and bioinformatics to overcome the limitation of library size in array-type screenings is reviewed.

Keywords: Cell assay, cell adhesion, cell proliferation, cell specificity, bioinformatics, Peptide array, animal-derived proteins, cellulose-bound peptide arrays


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