Abstract
Evidence accumulated to date indicates that inhibition of the renin-angiotensin system with angiotensin receptor blockers (ARB) may prevent new-onset of diabetes. ARB is also used for the prevention of occurrence and progression of complications in diabetes and diabetic nephropathy. From the results of recent large-scale clinical studies, ARB is considered as a first choice drug in hypertensive patients with diabetes. In this review article, we focus on the effects of ARB on progression and prevention against diabetes as a metabolic-improving agent.
Keywords: Metabolism, prevention, nephropathy, retinopathy
Current Vascular Pharmacology
Title: Pleiotropic Effects of ARB in Diabetes Mellitus
Volume: 9 Issue: 2
Author(s): Shu-ichi Saitoh and Yasuchika Takeishi
Affiliation:
Keywords: Metabolism, prevention, nephropathy, retinopathy
Abstract: Evidence accumulated to date indicates that inhibition of the renin-angiotensin system with angiotensin receptor blockers (ARB) may prevent new-onset of diabetes. ARB is also used for the prevention of occurrence and progression of complications in diabetes and diabetic nephropathy. From the results of recent large-scale clinical studies, ARB is considered as a first choice drug in hypertensive patients with diabetes. In this review article, we focus on the effects of ARB on progression and prevention against diabetes as a metabolic-improving agent.
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Cite this article as:
Saitoh Shu-ichi and Takeishi Yasuchika, Pleiotropic Effects of ARB in Diabetes Mellitus, Current Vascular Pharmacology 2011; 9 (2) . https://dx.doi.org/10.2174/157016111794519363
DOI https://dx.doi.org/10.2174/157016111794519363 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
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