Abstract
Perchloric acid immobilized on silica gel was used as an efficient and expedient catalyst for a very mild, synthesis of α-amino phosphonates by reaction of an aldehyde, amines and trialkylphosphite in acetonitrile at room temperature.
Keywords: Silica supported perchloric acid, α-amino phosphonates, Aldehydes, trialkylphosphite, acetonitrile, amino phosphonates, samarium diiodide, InCl3, (bromodimethyl)sulfonium bromide, LiClO4, montmorillonite, benzaldehyde, aniline, triethyl phosphite, MeOH, AVANCE spectrometer, Agilent Technology, Heraeus CHN-O-Rapid analyzer, NMR