Trifluoromethylation of Carbonyl Compounds

N.      Boechat; M.   M.   Bastos

doi:10.2174/157017910792246081

Abstract

This paper reviews the recent findings on trifluoromethylation of carbonyl compounds. Emphasis was given to the description of the trifluoromethylating agents, their activation mode, their reaction with carbonyl compounds, as well as applications in organic synthesis.

Keywords: Carbonyl compounds, nucleophilic reagents, sulfur tetrafluoride, TDAE, trifluoromethylation, trifluoromethyltrimethylsilane

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Current Organic Synthesis

Title: Trifluoromethylation of Carbonyl Compounds

Volume: 7 Issue: 5

Author(s): N. Boechat and M. M. Bastos

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Keywords: Carbonyl compounds, nucleophilic reagents, sulfur tetrafluoride, TDAE, trifluoromethylation, trifluoromethyltrimethylsilane

Abstract: This paper reviews the recent findings on trifluoromethylation of carbonyl compounds. Emphasis was given to the description of the trifluoromethylating agents, their activation mode, their reaction with carbonyl compounds, as well as applications in organic synthesis.

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Boechat N. and Bastos M. M., Trifluoromethylation of Carbonyl Compounds, Current Organic Synthesis 2010; 7 (5) . https://dx.doi.org/10.2174/157017910792246081