Abstract
The Morita-Morita-Baylis – Hillman reaction (MMBHR) is one of the most important carbon – carbon bond forming reactions, and involves the selective atom-economical construction of a carbon – carbon bond at the α-position of an activated alkene, providing densely functionalized molecules. One of the major drawbacks of the MBHR is the low reaction rate, requiring long reaction times. In this review, the MBHR, in combination with microwave irradiation is summarized for the synthesis of highly functionalized molecules with the advantages of green process and shorter reaction times.
Keywords: Microwave irradiation, Baylis-Hillman reaction, biological activity, DABCO, conventional heating, microwave effect, nonthermal effects
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
16